Category Archives: Uncategorized

Cis-regulatory evolution integrated the Bric-√†-brac transcription factors into a novel fruit fly gene regulatory network

Maxwell J Roeske, Eric M Camino, Sumant Grover, Mark Rebeiz, Thomas Michael Williams¬† Cite as: eLife 2018;7:e32273 doi: 10.7554/eLife.32273 Abstract Gene expression evolution through gene regulatory network (GRN) changes has gained appreciation as a driver of morphological evolution. However, understanding … Continue reading

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Using Drosophila pigmentation traits to study the mechanisms of cis-regulatory evolution

One primary agenda of the developmental evolution field is to elucidate molecular mechanisms governing differences in animal form. While mounting evidence has established an important role for mutations in transcription controlling cis-regulatory elements (CREs), the underlying mechanisms that translate these … Continue reading

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Drosophilaphilia #2: Silencing silencers to evolve new patterns

Drosophilaphilia #2: Silencing silencers to evolve new patterns.   Nice thoughtful overview on my collaborator’s new publication!

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Collaborators publish a study showing how evolutionary changes in a transcriptional silencer shaped the repeated evolution of a fruit fly trait. Might be a first description of a pervasive mechanism of evolutionary change!

Genetic Changes to a Transcriptional Silencer Element Confers Phenotypic Diversity within and between Drosophila Species Winslow C. Johnson , Alison J. Ordway , Masayoshi Watada, Jonathan N. Pruitt, Thomas M. Williams, Mark Rebeiz Author Summary One of the greatest challenges … Continue reading

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Eric Camino, John Butts and team get published in PLoS Genetics!!

The Evolutionary Origination and Diversification of a Dimorphic Gene Regulatory Network through Parallel Innovations in cis andtrans Eric M. Camino, John C. Butts, Alison Ordway, Jordan E. Vellky, Mark Rebeiz, Thomas M. Williams “Author Summary The genomic content of regulatory … Continue reading

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Tom Williams to speak at Pub Science 9/09/14

Tom Williams will tell the the Pub Science community about “Beyond the Birds and the Bees: Molecular Insights About the Making and Evolution of Fruit Fly Sexually Dimorphic Traits” on Tuesday September 9th. The presentation will begin at 7 PM … Continue reading

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2014 Midwest Ecology and Evolution Conference at UD (March 1st and 2nd, 2014)

                              http://meec2014.wordpress.com

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